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Št. zadetkov: 5
Izvirni znanstveni članek
Oznake: Copper;membrane transporter;molecular dynamics;QM/MM;free energy;
Copper is a trace element vital to many cellular functions. Yet its abnormal levels are toxic to cells, provoking a variety of severe diseases. The high affinity copper transporter 1 (CTR1), being the main in-cell copper [Cu(I)] entry route, tightly regulates its cellular uptake via a still elusive ...
Leto: 2022 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Izvirni znanstveni članek
Oznake: ion channels and transporters;intrinsically disordered regions;molecular dynamics;function regulation;
Intrinsically disordered ectodomain modulates ion permeation through a metal transporter
Leto: 2022 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Izvirni znanstveni članek
Oznake: Ctr1;copper;EPR;molecular dynamics;
Abnormal cellular copper levels have been clearly implicated in genetic diseases, cancer, and neurodegeneration. Ctr1, a high-affinity copper transporter, is a homotrimeric integral membrane protein that provides the main route for cellular copper uptake. Together with a sophisticated copper transpo ...
Leto: 2022 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Izvirni znanstveni članek
Oznake: biokemija;biološki procesi;baker;rakave celice;
Leto: 2022 Vir: Kemijski inštitut (KI)
Izvirni znanstveni članek
Oznake: CNG channels;pore flexibility;X-ray crystallography;MD simulations;
A structural, functional, and computational analysis suggests pore flexibility as the base for the poor selectivity of CNG channels
Leto: 2015 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Št. zadetkov: 5
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