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Št. zadetkov: 3
Heterogeneous response of airway eosinophilia to anti-IL-5 biologics in severe asthma patients
Maruša Kopač, Matija Rijavec, Peter Korošec, Urška Bidovec, Izidor Kern, Romana Vantur, Sabina Škrgat-Kristan, Sabina Škrgat-Kristan
Izvirni znanstveni članek
Oznake: težka astma;anti-IL-5 biološka zdravila;eozinofilija;dihalne poti;sputum;
Many questions concerning responders (R) and nonresponders (NR) in severe eosinophilic asthma (SEA) after blocking the IL-5 (interleukin 5) pathway are still not clear, especially regarding the early parameters of response to biologics in personalized treatment strategies. We evaluated 17 SEA patien ...
Leto: 2022 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Chemokines during anaphylaxis
Romana Vantur, Maruša Rihar, Ana Koren, Matija Rijavec, Peter Kopač, Urška Bidovec, Renato Eržen, Peter Korošec
Izvirni znanstveni članek
Oznake: CCL2;celična migracija;cell migration;
Background: The role of chemokines in anaphylaxis is unclear. Methods: We prospectively recruited 49 patients presenting to the emergency department with an acute episode of anaphylaxis and 28 healthy subjects. We measured serum levels of the chemokines CCL2, CCL5, CCL7, CCL8, CCL11, CCL13, CCL17, C ...
Leto: 2020 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Functional complement analysis can predict genetic testing results and long-term outcome in patients with complement deficiencies
Štefan Blazina, Maruša Debeljak, Mitja Košnik, Saša Simčič, Sanja Stopinšek, Gašper Markelj, Nataša Toplak, Peter Kopač, Breda Zakotnik, Marko Pokorn, Tadej Avčin
Izvirni znanstveni članek
Oznake: complement deficiency;primary immunodeficiency;laboratory analysis;genetic analysis;clinical manifestations;
Background: Prevalence of complement deficiencies (CDs) is markedly higher in Slovenian primary immunodeficiency (PID) registry in comparison to other national and international PID registries. Objective: The purposes of our study were to confirm CD and define complete and partial CD in registered ...
Leto: 2018 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Št. zadetkov: 3
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