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Št. zadetkov: 3
Computational design and characterization of nanobody-derived peptides that stabilize the active conformation of the [beta] [sub] 2-adrenergic receptor ([beta] [sub] 2-AR)
Milan Sencanski, Sanja Glisic, Nevena Veljkovic, Marko Šnajder, Nataša Poklar Ulrih, Janez Mavri, Milka Vrecl
Izvirni znanstveni članek
Oznake: nanotelesa;mimetiki;adrenergični beta receptorji;
This study aimed to design and functionally characterize peptide mimetics of the nanobody (Nb) related to the β2-adrenergic receptor (β2-AR) (nanobody-derived peptide, NDP). We postulated that the computationally derived and optimized complementarity-determining region 3 (CDR3) of Nb is sufficient f ...
Leto: 2019 Vir: Biotehniška fakulteta (UL BF)
Critical impact of different conserved endoplasmic retention mofits and dopamine receptor interacting proteins (DRIPs) on intracellular localization and trafficking of the D2 dopamine receptor (D2-R) isoforms
Kaja Blagotinšek Cokan, Maša Mavri, Catrin Rutland, Sanja Glisic, Milan Sencanski, Milka Vrecl, Valentina Kubale
Pregledni znanstveni članek
Oznake: D$_2$ dopamine receptor;intracellular trafficking;endoplasmic reticulum;retention motifs;ICL3;interacting partners;
The type 2 dopamine receptor D2 (D2-R), member of the G protein-coupled receptor (GPCR) superfamily, exists in two isoforms, short (D2S-R) and long (D2L-R). They differ by an additional 29 amino acids (AA) in the third cytoplasmic loop (ICL3) of the D2L-R. These isoforms differ in their intracellula ...
Leto: 2020 Vir: Medicinska fakulteta (UL MF)
Patterns of human and porcine gammaherpesvirus-encoded BILF1 receptor endocytosis
Maša Mavri, Sanja Glisic, Milan Sencanski, Milka Vrecl, Mette Marie Rosenklide, Katja Spiess, Valentina Kubale
Izvirni znanstveni članek
Oznake: Herpesvirus 4;human;Dynamins;Caveolins;beta-Arrestins;
Background: The viral G protein-coupled receptor (vGPCR) BILF1 encoded by the Epstein-Barr virus (EBV) is an oncogene and immunoevasin and can downregulate MHC-I molecules at the surface of infected cells. MHC-I downregulation, which presumably occurs through co-internalization with EBV-BILF1, is pr ...
Leto: 2023 Vir: Veterinarska fakulteta (UL VF)
Št. zadetkov: 3
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