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Št. zadetkov: 8
Morphological and immunocytochemical characterization of tumor spheroids in ascites from high-grade serous carcinoma
Simona Miceska, Erik Škof, Gorana Gašljević, Veronika Kloboves-Prevodnik
Izvirni znanstveni članek
Oznake: maligne celice;visokomaligni rak;rak jajčnikov;cell blocks;high-grade serous carcinoma;ovarian carcinoma;
Tumor spheroids in the ascites of high-grade serous carcinoma (HGSC) are poorly described. Our objective was to describe their morphological features, cellular composition, PD-1 and PD-L1 expression, and survival correlation of these parameters. The density and size of spheroids were assessed in Gie ...
Leto: 2023 Vir: Medicinska fakulteta (UM MF)
ǂThe ǂprognostic significance of tumor-immune microenvironment in ascites of patients with high-grade serous carcinoma
Simona Miceska, Erik Škof, Simon Buček, Cvetka Grašič-Kuhar, Gorana Gašljević, Špela Smrkolj, Veronika Kloboves-Prevodnik
Izvirni znanstveni članek
Oznake: visoko tvegani raki;imunske celice;biološki označevalci;napovedni označevalci;high-grade serous carcinoma;immune cells;prognostic markers;
Background: High-grade serous carcinoma (HGSC) is often associated with ascites at presentation. Our objective was to quantify immune cells (ICs) in ascites prior to any treatment was given and evaluate their impact on progression-free survival (PFS) and overall survival (OS). Patients and methods: ...
Leto: 2023 Vir: Onkološki inštitut Ljubljana (OI)
Morfološke značilnosti cirkulirajočih tumorskih celic raka dojk v krvi po izolaciji na podlagi njihovih fizikalnih ali bioloških lastnosti
Simona Miceska, Tanja Dolinšek, Živa Modic, Cvetka Grašič-Kuhar, Maja Čemažar, Urška Matkovič, Jerneja Varl, Anamarija Kuhar, Veronika Kloboves-Prevodnik
Objavljeni povzetek znanstvenega prispevka na konferenci
Oznake: citologija;diagnostika;onkologija;
Leto: 2022 Vir: Onkološki inštitut Ljubljana (OI)
Morphological features of breast cancer circulating tumor cells in blood after physical and biological type of isolation
Tanja Dolinšek, Živa Modic, Cvetka Grašič-Kuhar, Maja Čemažar, Urška Matkovič, Simona Miceska, Jerneja Varl, Anamarija Kuhar, Veronika Kloboves-Prevodnik
Izvirni znanstveni članek
Oznake: circulating tumor cells;breast cancer;morphology;
Background. Circulating tumor cells (CTCs) have become an important biomarker in breast cancer. Different iso-lation tech-niques based on their biological or physical features were established. Currently, the most widely used methods for visualization after their separation are based on immunofluore ...
Leto: 2021 Vir: Onkološki inštitut Ljubljana (OI)
Potentiation of electrochemotherapy effectiveness by immunostimulation with IL-12 gene electrotransfer in mice is dependent on tumor immune status
Katja Uršič, Špela Kos, Urška Kamenšek, Maja Čemažar, Simona Miceska, Boštjan Markelc, Simon Buček, Barbara Starešinič, Veronika Kloboves-Prevodnik, Richard Heller, Gregor Serša
Izvirni znanstveni članek
Oznake: elektrokemoterapija;elektroprenos genov;interlevkin-12;electrochemotherapy;gene electrotransfer;interleukin-12;
Electrochemotherapy (ECT) exhibits high therapeutic effectiveness in the clinic, achieving up to 80% local tumor control but without a systemic (abscopal) effect. Therefore, we designed a combination therapy consisting of ECT via intratumoral application of bleomycin, oxaliplatin or cisplatin with p ...
Leto: 2021 Vir: Onkološki inštitut Ljubljana (OI)
Nižje število cirkulirajočih tumorskih celic v poznih linijah razsejanega raka dojk
Silvester Jernej, Klara Geršak, Marina Mencinger, Tanja Ovčariček, Tanja Dolinšek, Živa Modic, Simona Miceska, Maja Čemažar, Veronika Kloboves-Prevodnik, Cvetka Grašič-Kuhar
Objavljeni povzetek strokovnega prispevka na konferenci
Oznake: onkologija;rak dojke;kemoterapija;
Leto: 2022 Vir: Onkološki inštitut Ljubljana (OI)
Association of circulating tumor cells, megakaryocytes and a high immune-inflammatory environment in metastatic breast cancer
Cvetka Grašič-Kuhar, Silvester Jernej, Marina Mencinger, Tanja Ovčariček, Maja Čemažar, Simona Miceska, Živa Modic, Anamarija Kuhar, Tanja Dolinšek, Veronika Kloboves-Prevodnik
Izvirni znanstveni članek
Oznake: rak dojke;kroženje tumorskih celic;preživetje;breast cancer;circulating tumor cell;overall survival;
Liquid biopsy is becoming an important source of new biomarkers during the treatment of metastatic cancer patients. Using size-based microfluid technology, we isolated circulating tumor cells (CTCs) from metastatic breast cancer patients to evaluate their presence and cluster formation, as well as t ...
Leto: 2023 Vir: Medicinska fakulteta (UM MF)
ǂThe ǂprognostic and predictive value of human gastrointestinal microbiome and exosomal mRNA expression of PD-L1 and IFNγ for immune checkpoint inhibitors response in metastatic melanoma patients
Ana Erman, Marija Ignjatović, Katja Leskovšek, Simona Miceska, Urša Lampreht Tratar, Maša Bošnjak, Veronika Kloboves-Prevodnik, Maja Čemažar, Lidija Kandolf Sekulović, Gorazd Avguštin, Janja Ocvirk, Tanja Mesti
Izvirni znanstveni članek
Oznake: gastrointestinalni mikrobiom;mRNA;imunski kontrolni zaviralci;metastatski melanom;gastrointestinal microbiome;mRNA expression of PD-L1 and IFNγ;immune checkpoint inhibitors;metastatic melanoma;
Background: Immunotherapy has been successful in treating advanced melanoma, but a large proportion of patients do not respond to the treatment with immune checkpoint inhibitors (ICIs). Preclinical and small cohort studies suggest gastrointestinal microbiome composition and exosomal mRNA expression ...
Leto: 2023 Vir: Onkološki inštitut Ljubljana (OI)
Št. zadetkov: 8
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