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Št. zadetkov: 24
Elektrogenska terapija z interlevkinom 12 za zdravljenje kožnih in oralnih tumorjev pri psih
Urša Lampreht Tratar, Maja Čemažar
Doktorska disertacija
Oznake: genski elektroprenos interlevkin 12 veterinarska onkologija pasje maligne melanomske celične linije klinična študija;
Znanstveno izhodišče: Spontani tumorji pri psih predstavljajo odličen model za preizkušanje novih terapij in za njihov prenos v humano onkologijo. Ena izmed novih terapij, ki se je izkazala za izredno učinkovito za zdravljenje tumorjev pri psih in ljudeh je elektrokemoterapija. Elektrokemoterapija j ...
Leto: 2018 Vir: Medicinska fakulteta (UL MF)
Book of abstracts
Gregor Serša, Ibrahim Edhemović, Simona Kranjc, Maša Bošnjak, Urša Lampreht Tratar
Zbornik strokovnih ali nerecenziranih znanstvenih prispevkov na konferenci
Oznake: bleomicin;melanom;rak glave in vratu;elektroporacija;zborniki;povzetki;
Book of abstracts
Leto: 2018 Vir: Onkološki inštitut Ljubljana (OI)
Adjuvant TNF-a therapy to electrochemotherapy with intravenous cisplatin in murine sarcoma exerts synergistic antitumor effectiveness
Vesna Todorović, Maja Čemažar, Urška Kamenšek, Urša Lampreht Tratar, Simona Kranjc, Andrej Cör, Gregor Serša, Janez Ščančar, Monika Štimac, Maja Čemažar, Vesna Todorović, Janez Ščančar, Urša Lampreht Tratar, Monika Savarin, Urška Kamenšek, Simona Kranjc Brezar, Andrej Cör, Gregor Serša
Izvirni znanstveni članek
Oznake: electrochemotherapy;TNF;adjuvant immunotherapy;cisplatin;
Background. Electrochemotherapy is a tumour ablation modality, based on electroporation of the cell membrane, allowing non-permeant anticancer drugs to enter the cell, thus augmenting their cytotoxicity by orders of magnitude. In preclinical studies, bleomycin and cisplatin proved to be the most sui ...
Leto: 2015 Vir: Univerza v Ljubljani (UL)
Health-related quality of life in dogs treated with electrochemotherapy and/or interleukin-12 gene electrotransfer
Nina Milevoj, Nataša Tozon, Sabina Ličen, Urša Lampreht Tratar, Gregor Serša, Maja Čemažar
Izvirni znanstveni članek
Oznake: Dogs;electrochemotherapy;gene electrotransfer;health;interleukin-12;
The aim of this study was to evaluate the owners' perception of health-related qual- ity of life (HRQoL) of dogs after treatment with electrochemotherapy (ECT) alone or combined with interleukin-12 gene electrotransfer (IL-12 GET) and/or surgery. The owners of 44 dogs with histologically differ ...
Leto: 2020 Vir: Veterinarska fakulteta (UL VF)
Electroporation - based treatments in small animal veterinary oral and maxillofacial oncology
Ana Nemec, Nina Milevoj, Urša Lampreht Tratar, Gregor Serša, Maja Čemažar, Nataša Tozon
Pregledni znanstveni članek
Oznake: Electroporation;electrochemotherapy (ECT);gene electrotransfer;oral tumors;dog;cats;
Electroporation is a method of inducing an increase in permeability of the cell membrane through the application of an electric field and can be used as a delivery method for introducing molecules of interest (e.g., chemotherapeutics or plasmid DNA) into cells. Electroporation-based treatments (i.e. ...
Leto: 2020 Vir: Veterinarska fakulteta (UL VF)
Pharmacokinetics of carprofen in anaesthetized pigs
Maša Bošnjak, Mojca Kržan, Urša Lampreht Tratar, Jožica Dolenc, Maja Čemažar, Alenka Seliškar
Izvirni znanstveni članek
Oznake: Carprofen;pharmacokinetics;swine;
Objective To investigate the pharmacokinetics of carprofen after a single intravenous (IV) dose and multiple oral doses administered to pigs undergoing electroporation of the pancreas. Study design Prospective experimental study. Animals A group of eight female pigs weighing 31.74 ± 2.24 kg (me ...
Leto: 2021 Vir: Medicinska fakulteta (UL MF)
Intoxication in a pig (Sus scrofa domesticus) after transdermal fentanyl patch ingestion
Jerneja Sredenšek, Maša Bošnjak, Urša Lampreht Tratar, Tina Kosjek, Maja Čemažar, Mojca Kržan, Alenka Seliškar
Izvirni znanstveni članek
Oznake: intoxication;pharmacokinetics;naloxone-opioid overdose;swine;pig;fentanyl transdermal patch;pharmacological phenomena;toxicological phenomena;fentanyl;
An experimental study on the effects of electroporation on pancreatic tissue was performed in pigs, and the fentanyl transdermal patch (FTP) was used postoperatively as part of multimodal pain management. Ingestion of an FTP, which resulted in fentanyl intoxication, was suspected 5 days after placem ...
Leto: 2020 Vir: Veterinarska fakulteta (UL VF)
Palliative jaw-sparing treatment of a non-resectable canine oral fibrosarcoma using combination of electrochemotherapy with bleomycin and IL-12 gene electrotransfer
Darja Pavlin, Ana Nemec, Urša Lampreht Tratar, Maja Čemažar, Andreja Brožič, Gregor Serša, Nataša Tozon
Izvirni znanstveni članek
Oznake:
Abstract: A 15-year-old male castrated English setter was presented for evaluation of a rapidly growing oral mass. Patient’s history was otherwise unremarkable, except of moderate proteinuria of 5 years duration. Clinical examination findings were within normal limits, except of an ulcerated located ...
Leto: 2021 Vir: Veterinarska fakulteta (UL VF)
Razvoj avtologne tumorske vakcine pripravljene z obsevanjem
Tinkara Remic, Gregor Serša, Katja Uršič, Kristina Levpušček, Urša Lampreht Tratar, Maja Čemažar, Urška Kamenšek
Objavljeni povzetek znanstvenega prispevka na konferenci
Oznake: onkološka cepiva;tumorski antigeni;eksperimentalna onkologija;
Razvoj avtologne tumorske vakcine pripravljene z obsevanjem
Leto: 2022 Vir: Onkološki inštitut Ljubljana (OI)
Tumor cell-based vaccine contributes to local tumor irradiation by eliciting a tumor model-dependent systemic immune response
Tinkara Remic, Gregor Serša, Kristina Levpušček, Urša Lampreht Tratar, Katja Uršič, Andrej Cör, Urška Kamenšek
Izvirni znanstveni članek
Oznake: eksperimentalna onkologija;multimodalno zdravljenje;radio-imunoterapija;experimental oncology;multimodal treatment;radio-imunotherapy;
Multimodal treatment approaches, such as radio-immunotherapy, necessitate regimen optimization and the investigation of the interactions of different modalities. The aim of this study was two-fold. Firstly, to select the most effective combination of irradiation and the previously developed tumor ce ...
Leto: 2022 Vir: Onkološki inštitut Ljubljana (OI)
Št. zadetkov: 24
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