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Št. zadetkov: 9
Vrednotenje postopkov elektrokemoterapije in genskega elektroprenosa plazmidne DNA z zapisom za pasji interlevkin-12 pri zdravljenju spontanih kožnih in oralnih tumorjev pri psih
Nina Milevoj, Nataša Tozon
Doktorska disertacija
Oznake: veterinarska onkologija;elektrokemoterapija;genski elektroprenos;bleomicin;interlevkin-12;kakovost življenja pri psih;
Namen doktorske naloge je bil vrednotenje postopkov elektrokemoterapije (EKT) in genskega elektroprenosa (GEP) plazmidne DNA z zapisom za pasji interlevkin-12 (IL-12) pri zdravljenju spontanih kožnih in oralnih tumorjev pri psih. S tekočinsko kromatografijo, sklopljeno s tandemsko masno spektrometri ...
Leto: 2020 Vir: Veterinarska fakulteta (UL VF)
Metronomic chemotherapy for palliative treatment of malignant oral tumors in dogs
Nina Milevoj, Ana Nemec, Nataša Tozon
Izvirni znanstveni članek
Oznake: metronomic chemotherapy;cyclophosphamide;malignant oral tumors;dogs;palliative treatment;drug therapy;neoplasms;palliative care;
The aim of this study was to evaluate the efficacy of metronomic chemotherapy in the palliative treatment of various malignant oral tumors in dogs. Our focus was to determine the effect of treatment on local disease control and to assess the tolerability and safety of the treatment in dogs with vari ...
Leto: 2022 Vir: Veterinarska fakulteta (UL VF)
Health-related quality of life in dogs treated with electrochemotherapy and/or interleukin-12 gene electrotransfer
Nina Milevoj, Nataša Tozon, Sabina Ličen, Urša Lampreht Tratar, Gregor Serša, Maja Čemažar
Izvirni znanstveni članek
Oznake: Dogs;electrochemotherapy;gene electrotransfer;health;interleukin-12;
The aim of this study was to evaluate the owners' perception of health-related qual- ity of life (HRQoL) of dogs after treatment with electrochemotherapy (ECT) alone or combined with interleukin-12 gene electrotransfer (IL-12 GET) and/or surgery. The owners of 44 dogs with histologically differ ...
Leto: 2020 Vir: Veterinarska fakulteta (UL VF)
Electroporation - based treatments in small animal veterinary oral and maxillofacial oncology
Ana Nemec, Nina Milevoj, Urša Lampreht Tratar, Gregor Serša, Maja Čemažar, Nataša Tozon
Pregledni znanstveni članek
Oznake: Electroporation;electrochemotherapy (ECT);gene electrotransfer;oral tumors;dog;cats;
Electroporation is a method of inducing an increase in permeability of the cell membrane through the application of an electric field and can be used as a delivery method for introducing molecules of interest (e.g., chemotherapeutics or plasmid DNA) into cells. Electroporation-based treatments (i.e. ...
Leto: 2020 Vir: Veterinarska fakulteta (UL VF)
Results of dynamic contrast-enhanced ultrasound correlate with treatment outcome in canine neoplasia treated with electrochemotherapy and interleukin-12 plasmid electrotransfer
Maja Brložnik, Simona Kranjc, Nina Boc, Tanja Knific, Maja Čemažar, Nina Milevoj, Gregor Serša, Nataša Tozon, Darja Pavlin
Izvirni znanstveni članek
Oznake: dog;contrast-enhanced ultrasonography;electrochemotherapy;immunotherapy;gene electrotransfer;bleomycin;cisplatin;IL-12 plasmid;
Electrochemotherapy (ECT) and/or gene electrotransfer of plasmid DNA encoding interleukin-12 (GET pIL-12) are effective treatments for canine cutaneous, subcutaneous, and maxillofacial tumors. Despite the clinical efficacy of the combined treatments of ECT and GET, data on parameters that might pred ...
Leto: 2021 Vir: Veterinarska fakulteta (UL VF)
ǂA ǂcombination of electrochemotherapy, gene electrotransfer of plasmid encoding canine IL-12 and cytoreductive surgery in the treatment of canine oral malignant melanoma
Nina Milevoj, Urša Lampreht Tratar, Ana Nemec, Andreja Brožič, Katarina Žnidar, Gregor Serša, Maja Čemažar, Nataša Tozon
Izvirni znanstveni članek
Oznake: electrochemotherapy;surgery;oral;interleukin-12;cytoreductive surgery;oral malignant melanoma;regulatory T cells;dogs;
The aim of this study was to evaluate the safety and efficacy of the combination of electrochemotherapy (ECT) with bleomycin and gene electrotransfer (GET) of plasmid encoding canine interleukin 12 (IL-12) for the treatment of canine oral malignant melanoma (OMM). Our focus was to determine the effe ...
Leto: 2019 Vir: Veterinarska fakulteta (UL VF)
Comparison of nucleosome, ferritin and LDH levels in blood with clinical response before and after electrochemotherapy combined with IL-12 gene electrotransfer for the treatment of mast cell tumours in dogs
Maša Vilfan, Urša Lampreht Tratar, Nina Milevoj, Alenka Nemec Svete, Maja Čemažar, Gregor Serša, Nataša Tozon
Izvirni znanstveni članek
Oznake: electrochemotherapy;Interleukin-12;mast cells;neoplasms;biomarkers;nucleosomes;ferritins;L-Lactate dehydrogenase;
Electrochemotherapy (ECT) in combination with the gene electrotransfer of interleukin 12 (IL-12 GET) has been successfully used in veterinary medicine for the treatment of mast cell tumours (MCT), but the biomarkers that could predict response to this treatment have not yet been investigated. The ai ...
Leto: 2024 Vir: Veterinarska fakulteta (UL VF)
Safety and feasibility of electrochemotherapy of the pancreas in a porcine model
Rok Dežman, Maja Čemažar, Gregor Serša, Alenka Seliškar, Vladimira Erjavec, Blaž Trotovšek, Gorana Gašljević, Maša Bošnjak, Urša Lampreht Tratar, Bor Kos, Mihajlo Djokić, Nina Milevoj, Marina Štukelj, Nina Boc, Jani Izlakar, Peter Popović
Izvirni znanstveni članek
Oznake: elektrokemoterapija;elektroporacija;pankreas;rak trebušne slinavke;prašiči;electrochemotherapy;electroporation;pancreas;porcine;pancreatic carcinoma;
Objectives: The use of thermal ablative therapies in the pancreatic tumors is limited because of the risk of the vessel injury and potential pancreatitis or fistula formation. Electrochemotherapy (ECT) is an ablative therapy with established role in the treatment of cutaneous and liver tumors. This ...
Leto: 2020 Vir: Repozitorij Univerze v Ljubljani (RUL)
Genska terapija v onkologiji, prvi razvojni koraki v Sloveniji
Maja Čemažar, Tanja Dolinšek, Maša Bošnjak, Boštjan Markelc, Urška Kamenšek, Simona Kranjc, Špela Kos, Urša Lampreht Tratar, Katarina Žnidar, Andrej Renčelj, Urška Matkovič, Teja Valant, Kristina Levpušček, Živa Modic, Tilen Komel, Tim Božič, Urša Kešar, Barbara Starešinič, Katja Uršič, Monika Štimac, Primož Strojan, Gorana Gašljević, Maja Ota, Aleš Grošelj, Črt Jamšek, Rosana Hudej, Matjaž Peterka, Franc Smrekar, Barbara Hubad, Marjan Hosta, Jaka Kužnik, Alojz Hosta, Damijan Miklavčič, Matej Reberšek, Aleksandra Cvetkoska, Anja Zajc, Janja Dermol-Černe, Nataša Tozon, Nina Milevoj, Alenka Nemec Svete, Gregor Serša
Strokovni članek
Oznake: genska terapija;interlevkin-12;plazmidna DNA;elektroprenos genov;rak kože;
Genska terapija postaja čedalje bolj zanimiva tudi v onkologiji. Med aplikacijami je morda najzanimivejša imunostimulacija. Pripravimo lahko plazmidno DNA, ki nosi zapis za različne imunostimulatorne molekule, ki jih vnesemo v celice tumorjev ali normalnih tkiv. Ta tkiva postanejo proizvajalci teh m ...
Leto: 2022 Vir: Onkološki inštitut Ljubljana (OI)
Št. zadetkov: 9
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