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Št. zadetkov: 6
Genetic variation of the mitochondrial D-loop region containing mitochondrial transcription factor (TFAM) binding sites is not associated with marbling in Wagyu X Limousin F2 crosses
Tanja Kunej, Jennifer J. Michal, Peter Dovč, Zhihua Jiang
Kratki znanstveni prispevek
Oznake: cattle;breeds;Limousin;Wagyu;crosses;molecular genetics;mitochondrial transcription factor;mtDNA;muscles;marbling;
Mitochondrial transcription factor A (TFAM) is a nucleus-encoded protein that is essential for initiation of transcription and replication of mitochondrial DNA (mtDNA). It has been shown that TFAM binds the entire length of the mtDNA,but with higher affinitz to sequences around both mitochondrial pr ...
Leto: 2005 Vir: Biotehniška fakulteta (UL BF)
ǂThe ǂglypican 3-hosted murine Mir717 gene
Tanja Kunej, Daša Jevšinek Skok, Simon Horvat, Peter Dovč, Zhihua Jiang
Izvirni znanstveni članek
Oznake: molekularna genetika;geni;Mir717;
Mir717 (mmu-mir-717) was first reported in mouse and resides in the intron 3 of glypican 3 )Gpc3) gene. Our present study revealed that this microRNA (miRNA) gene is conserved among 26 mammalian species and harbors polymorphic sites within the mature seed region in mice. Our findiong represents a ra ...
Leto: 2010 Vir: Biotehniška fakulteta (UL BF)
Differential alternative polyadenylation response to high-fat diet between polygenic obese and healthy lean mice
Špela Mikec, Simon Horvat, Hongyang Wang, Jennifer J. Michal, Tanja Kunej, Zhihua Jiang
Izvirni znanstveni članek
Oznake: laboratorijske miši;poligeni modeli;debela linija;vitka linija;genetika;poliadenilacija;prehrana živali;krma;maščobe;
Obesity's complex etiology due to the interplay of environment and genetics makes it a more challenging research and health problem. Some of the contributing genetic factors that have not yet been examined in detail entail mRNA polyadenylation (PA). Genes with multiple PA sites express mRNA isoforms ...
Leto: 2023 Vir: Biotehniška fakulteta (UL BF)
Cross species association examination of UCN3 and CRHR2 as potential pharmacological targets for antiobesity drugs
Zhihua Jiang, Jennifer J. Michal, Galen A. Williams, Tyler F. Daniels, Tanja Kunej
Izvirni znanstveni članek
Oznake: molekularna genetika;debelost;farmacija;
Cross species association examination of UCN3 and CRHR2 as potential pharmacological targets for antiobesity drugs
Leto: 2006 Vir: Biotehniška fakulteta (UL BF)
Obesity gene atlas in mammals
Tanja Kunej, Daša Jevšinek Skok, Minja Zorc, Ana Ogrinc, Jennifer J. Michal, Milena Kovač, Zhihua Jiang
Izvirni znanstveni članek
Oznake: molekularna genetika;baze podatkov;geni;debelost;sesalci;
Obesity in humans has increased at an alarming rate over the past two decades and has become one of the leading public health problems worldwide. Studies have revealed a large number of genes/markers that are associated with obesity and/or obesity-related phenotypes, indicating an urgent need to dev ...
Leto: 2013 Vir: Biotehniška fakulteta (UL BF)
Catalog of MicroRNA seed polymorphisms in vertebrates
Minja Zorc, Daša Jevšinek Skok, Irena Godnič, George A. Calin, Simon Horvat, Zhihua Jiang, Peter Dovč, Tanja Kunej
Izvirni znanstveni članek
Oznake: molekularna genetika;mikro RNK;polimorfizem;bioinformatika;vretenčarji;
MicroRNAs (miRNAs) are a class of non-coding RNA that plays an important role in posttransriptional regulation of mRNA. Evidence has shown that miRNA gene variability might interfere with its function resulting in phenotypic variation and disease susceptibility. A major role in miRNA target recognit ...
Leto: 2012 Vir: Biotehniška fakulteta (UL BF)
Št. zadetkov: 6
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