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ǂThe ǂsearch for novel proline analogs for viscosity reduction and stabilization of highly concentrated monoclonal antibody solutions
Monika Prašnikar, Matic Proj, Maja Bjelošević, Blaž Lebar, Benjamin Knez, Nika Osel, Robert Roškar, Stanislav Gobec, Iztok Grabnar, Aleš Žula, Pegi Ahlin Grabnar
Izvirni znanstveni članek
Oznake: proline analogs;monoclonal antibodies;subcutaneous administration;viscosity reducers;high concentration;
Administration of monoclonal antibodies (mAbs) is currently focused on subcutaneous injection associated with increased patient adherence and reduced treatment cost, leading to sustainable healthcare. The main bottleneck is low volume that can be injected, requiring highly concentrated mAb solutions ...
Leto: 2024 Vir: Fakulteta za farmacijo (UL FFA)
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