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Lipidation of NOD2 agonists with adamantane and stearoyl moieties differentially regulates their In vivo adjuvant activity
Samo Guzelj, Marcela Šišić, Špela Bizjak, Leo Frkanec, Ruža Frkanec, Žiga Jakopin
Izvirni znanstveni članek
Oznake: agonisti NOD2;adjuvans za cepivo;adamantan;imunopotenciatorji;desmuramilpeptidi;NOD2 agonist;vaccine adjuvant;adamantane;immunopotentiators;desmuramylpeptides;
NOD2 is an innate immune receptor that constitutes an important target for the development of small molecule immunopotentiators with great potential to be used as vaccine adjuvants. We report here the results of an in vivo study of the adjuvant properties of a desmuramylpeptide NOD2 agonist SG29 and ...
Leto: 2022 Vir: Fakulteta za farmacijo (UL FFA)
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