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Št. zadetkov: 7
Vloga cisteinske peptidaze katepsina X pri polarizaciji celic mikroglije
Klara Verbič, Anja Hafner, Lara Bolčina
Magistrsko delo
Oznake: mikroglija;polarizacija;vnetje;katepsin X;zaviralec katepsina X;
Celice mikroglije so glialne celice centralnega živčnega sistema (CŽS), podobne makrofagom, ki vzdržujejo homeostazo možganov in so ene izmed najpomembnejših prirojenih celic imunskega sistema v CŽS. Pod vplivom patoloških in imunoloških dražljajev pride do polarizacije mikroglije v pro-vnetni fenot ...
Leto: 2022 Vir: Fakulteta za farmacijo (UL FFA)
Amphiphilic coumarin-based probes for live-cell STED nanoscopy of plasma membrane
Hana Majaron, Boštjan Kokot, Anja Hafner, Hana Esih, Alen Gabrič, Dunja Urbančič, Rojbin El, Iztok Urbančič, Stane Pajk
Izvirni znanstveni članek
Oznake: fizika;membrane;fluorescenca;
Plasma membranes are vital biological structures, serving as protective barriers and participating in various cellular processes. In the field of super-resolution optical microscopy, stimulated emission depletion (STED) nanoscopy has emerged as a powerful method for investigating plasma membrane-rel ...
Leto: 2024 Vir: Institut Jožef Stefan (IJS)
Transforming ureas into carbamates
Svit Ferjančič Benetik, Anže Meden, Damijan Knez, Peter Mastnak-Sokolov, Urban Košak, Selena Horvat, Anja Hafner, Rudolf Andrys, Aleš Obreza, Stanislav Gobec
Izvirni znanstveni članek
Oznake: butyrylcholinesterase;p38α mitogen-activated protein kinase;dual inhibitors;carbamate;pseudo-irreversible inhibition;
Given the limited benefits of anticholinergic drugs and the repeated clinical failures of anti-amyloid therapies, the therapeutic focus in Alzheimer's disease (AD) is gradually shifting toward addressing both disease symptoms and its major underlying cause – neuroinflammation. We have developed nove ...
Leto: 2025 Vir: Fakulteta za farmacijo (UL FFA)
Targeting neuroinflammation and cognitive decline
Svit Ferjančič Benetik, Matic Proj, Damijan Knez, Urban Košak, Anže Meden, Katja Krajšek, Anja Hafner, Selena Horvat, Urban Švajger, Nataša Tešić, Aleš Obreza, Stanislav Gobec
Izvirni znanstveni članek
Oznake: central nervous system;inhibition;inhibitors;peptides and proteins;rodent models;
The currently approved drugs for the treatment of Alzheimer’s disease (AD) fail to address its interconnected pathological processes. Inhibition of butyrylcholinesterase (BChE) and p38α mitogen-activated protein kinase (p38α MAPK) offers an innovative dual approach to mitigate two major drivers of n ...
Leto: 2025 Vir: Fakulteta za farmacijo (UL FFA)
Strah pred izgubo zaposlitve
Anja Lazar, Mitja Hafner-Fink
Diplomsko delo
Oznake: Zaposlitev;Trg dela;Brezposelnost;Strah;Socialna država;
Strah pred izgubo zaposlitve
Leto: 2009 Vir: Fakulteta za družbene vede (UL FDV)
Vzgoja za zdravo spolnost z vidika mladostnikov
Anja Kožar, Tanja Torkar, Alenka Hafner, Katja Skinder Savić
Diplomsko delo
Oznake:
Vzgoja za zdravo spolnost z vidika mladostnikov
Leto: 2014 Vir: Visoka šola za zdravstveno nego Jesenice (VŠZNJ)
Self-assembled structures composed of single polypeptide comprising at least three coiled-coil forming elements
Roman Jerala, Ota Fekonja, Jelka Pohar, Helena Gradišar, Mojca Benčina, Iva Hafner Bratkovič, Robert Bremšak, Špela Miklavič, Urška Jelerčič, Anja Lukan, Tibor Doles, Sabina Božič, Marko Verce, Nika Debeljak, Jožica Friedrich
Patent
Oznake: analizna kemija;polipeptidne verige;samosestavljive strukture;obvite vijačnice;self assembled structures;polipeptide chain;nenostructures;
Self-assembled structures composed of single polypeptide comprising at least three coiled-coil forming elements
Leto: 2014 Vir: Kemijski inštitut (KI)
Št. zadetkov: 7
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