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Št. zadetkov: 11
Sustained delivery of Cu(II)-based DNA intercalators by nanometer-sized cyclodextrin-based porous polymers
Tina Škorjanc, Julian Heinrich, Damjan Makuc, Nora Kulak, Matjaž Valant
Izvirni znanstveni članek
Oznake: porous organic polymers;cyclodextrin;DNA intercalators;Cu(II) complexes;metal complexes;
DNA intercalators are small molecules that insert between adjacent DNA base pairs and thus disturb DNA replication and transcription, which can lead to cell death. Certain metal complexes are excellent DNA intercalators, and have shown promise in chemotherapy. Here, a cyclodextrin porous polymer was ...
Leto: 2023 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
ǂA ǂkinetic approach in the evaluation of radical-scavenging efficiency of sinapic acid and its derivates
Neda Martinović, Tomaž Polak, Damjan Makuc, Nataša Poklar Ulrih, Helena Abramovič
Izvirni znanstveni članek
Oznake: organske kisline;fenolne kisline;sinapinske kisline;sinapin;antioksidativna učinkovitost;DPPH;lovilci prostih radikalov;
A kinetic approach was used to determine the radical scavenging activities of sinapic acid and its derivatives: sinapine, 4-vinylsyringol, syringic acid, syringaldehyde, and ethyl, propyl and butyl sinapate. The responses were expressed as rates of 2,2-diphenyl-1-picrylhydrazyl radical (DPPH$^·$) sc ...
Leto: 2017 Vir: Biotehniška fakulteta (UL BF)
Children gut microbiota exhibits a different composition and metabolic profile after in vitro exposure to Clostridioides difficile and increases its sporulation
Sabina Horvat, Aleksander Mahnič, Damjan Makuc, Klemen Pečnik, Janez Plavec, Maja Rupnik
Izvirni znanstveni članek
Oznake: biokemija;črevesna mikrobiota;črevesna flora;presnova;metabolizem;otroci;
Clostridioides difficile (Clostridium difficile) infection (CDI) is one of the main public health concerns in adults, while children under 2 years of age are often colonized asymptomatically. In both adults and children, CDI is strongly associated with disturbances in gut microbiota. In this study, ...
Leto: 2022 Vir: Medicinska fakulteta (UM MF)
In vitro tumor hypoxia imaging with fluorescent covalent organic frameworks
Tina Škorjanc, Dinesh Shetty, Damjan Makuc, Gregor Mali, Martina Bergant Marušič, Matjaž Valant
Objavljeni povzetek znanstvenega prispevka na konferenci
Oznake: kemija;biokemija;slikanje;tumorji;rakave celice;hypoxia;fluorescence;covalent organic frameworks;imaging;tumor cells;
Hypoxia refers to a condition where cells and tissues experience low, inadequate levels of O2. While healthy tissues are typically supplied with sufficient O2 (normoxia), cancerous tissues commonly face hypoxia due to the tumor’s extraordinarily high demand for oxygen. Various fluorescent small-mole ...
Leto: 2023 Vir: Univerza v Novi Gorici (UNG)
Covalent organic frameworks for fluorescent imaging of hypoxia
Tina Škorjanc, Dinesh Shetty, Gregor Mali, Damjan Makuc, Martina Bergant Marušič, Matjaž Valant
Objavljeni povzetek znanstvenega prispevka na konferenci
Oznake: hypoxia;covalent organic frameworks;imaging;fluorescence;post-synthetic modification;
Covalent organic frameworks for fluorescent imaging of hypoxia
Leto: 2023 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Cytotoxicity and antibacterial efficacy of betaine- and choline-substituted polymers
Lucija Jurko, Damjan Makuc, Alja Štraser, Janez Plavec, Bojana Žegura, Perica Bošković, Rupert Kargl
Izvirni znanstveni članek
Oznake: kemija;polimeri;antimikrobi;antibakterijska sredstva;hydroxyethyl cellulose;polyvinyl alcohol;antimicrobial;S. aureus;P. aeruginosa;L929 mouse fibroblast;cationic polymer;
Cationic charge has been widely used to increase polymer adsorption and flocculation of dispersions or to provide antimicrobial activity. In this work, cationization of hydroxyethyl cellulose (HEC) and polyvinyl alcohol (PVA) was achieved by covalently coupling betaine hydrochloride and choline chlo ...
Leto: 2023 Vir: Kemijski inštitut (KI)
Co-crystals, salts or mixtures of both? The case of tenofovir alafenamide fumarates
Hannes Lengauer, Damjan Makuc, Damjan Šterk, Franc Perdih, Arthur Pichler, Tina Trdan Lušin, Janez Plavec, Zdenko Časar
Izvirni znanstveni članek
Oznake: co-crystal;salt;polymorphism;X-ray dffraction;
Tenofovir alafenamide fumarate (TAF) is the newest prodrug of tenofovir that constitutes several drug products used for the treatment of HIV/AIDS. Although the solid-state properties of its predecessor tenofovir disoproxil fumarate have been investigated and described in the literature, there are no ...
Leto: 2020 Vir: Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
Efficiency of neat and quaternized-cellulose nanofibril fillers in chitosan membranes for direct ethanol fuel cells
Maša Hren, Damjan Makuc, Janez Plavec, Michaela Roschger, Viktor Hacker, Boštjan Genorio, Mojca Božič, Selestina Gorgieva
Izvirni znanstveni članek
Oznake: hitozan;celulozni nanofibrili;anionsko izmenjevalne membrane;alkoholne gorivne celice;chitosan;cellulose nanofibrils;anion exchange membrane;direct alkaline alcohol fuel cells;
Leto: 2023 Vir: Fakulteta za strojništvo (UM FS)
Nitroreductase-sensitive fluorescent covalent organic framework for tumor hypoxia imaging in cells
Tina Škorjanc, Dinesh Shetty, Sushil Kumar, Damjan Makuc, Gregor Mali, Janez Volavšek, Martina Bergant Marušič, Matjaž Valant
Izvirni znanstveni članek
Oznake: covalent organic frameworks;imaging;hypoxia;fluorescence;cancer cells;
Nitroreductase-sensitive fluorescent covalent organic framework for tumor hypoxia imaging in cells
Leto: 2023 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Hyaluronic acid conjugates of glycine peptides and L-tryptophan
Fazilet Gürer, Tamilselvan Mohan, Matej Bračič, Ariana Barlič, Damjan Makuc, Janez Plavec, Karin Stana-Kleinschek, Rupert Kargl
Izvirni znanstveni članek
Oznake: biokemija;peptidi;spektroskopija;raziskave;
Leto: 2024 Vir: Kemijski inštitut (KI)
Št. zadetkov: 11
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