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Št. zadetkov: 9
Rokomet na mivki
Jaka Peterlin, Marko Šibila, Marta Bon
Diplomsko delo
Oznake: šport;rokomet na mivki;zgodovina;razvoj;pravila igre;metodika poučevaja;tehnični elementi;taktični elementi;slovenski izrazi;
Rokomet na mivki je v primerjavi z ostalimi športi športna igra s kratko zgodovino. Njen razvoj se je začel v devetdesetih letih prejšnjega stoletja na jugu Italije. Gre za različico dvoranskega rokometa z mnogimi spremembami in prilagoditvami, kot so velikost igrišča, število igralcev na igrišču, m ...
Leto: 2019 Vir: Fakulteta za šport (UL FŠ)
Unimodalna kategorija in topološka statistika
Jakob Peterlin, Jaka Smrekar
Diplomsko delo
Oznake: matematika;unimodalna kategorija;unimodalna dekompozicija;homotopija;
Unimodalna kategorija in topološka statistika
Leto: 2015 Vir: Fakulteta za matematiko in fiziko (UL FMF)
Analiza funkcij managementa na primeru domače kmetije
Marta Jaki, Judita Peterlin
Diplomsko delo
Oznake: kmetijstvo;kmetje;podjetje;management;manager;poslovne odločitve;primeri;analiza;
Analiza funkcij managementa na primeru domače kmetije
Leto: 2019 Vir: Ekonomska fakulteta (UL EF)
Structure-activity relationships of benzothiazole-based Hsp90 C-terminal-domain inhibitors
Jaka Dernovšek, Živa Zajec, Martina Durcik, Lucija Peterlin-Mašič, Martina Gobec, Nace Zidar, Tihomir Tomašić
Izvirni znanstveni članek
Oznake: zaviralci;benzotiazol;alosterija;allosteric;Hsp90;benzothiazole;cancer;inhibitor;cancer therapy;
Heat shock protein 90 (Hsp90) is a chaperone responsible for the maturation of many cancer-related proteins, and is therefore an important target for the design of new anticancer agents. Several Hsp90 N-terminal domain inhibitors have been evaluated in clinical trials, but none have been approved as ...
Leto: 2021 Vir: Fakulteta za farmacijo (UL FFA)
ǂThe ǂfirst subacute study with oral administration of bisphenol AP in male rats
Přemysl Mladěnka, Jaka Fadraersada, Patrícia Dias, Václav Tvrdý, Jana Pourová, Eduard Jirkovský, Alejandro Carazo, Marija Sollner Dolenc, Jurij Trontelj, Lucija Peterlin-Mašič
Izvirni znanstveni članek
Oznake: bisphenol;endocrine disruptor;pollutant;hypertension;cardiovascular;
Bisphenols are frequently used in the plastic industry. However, there is a need for addressing their safety in in vivo studies based on the observed negative impact of bisphenol A. Bisphenol AP (BPAP) is frequently found in the environment, human food, and biological fluids, but its cardiovascular ...
Leto: 2025 Vir: Fakulteta za farmacijo (UL FFA)
New diarylamine KV10.1 inhibitors and their anticancer potential
Špela Gubič, Žan Toplak, Xiaoyi Shi, Jaka Dernovšek, Louise Antonia Hendrickx, Ernesto Lopes Pinheiro-Junior, Steve Peigneur, Jan Tytgat, Luis A. Pardo, Lucija Peterlin-Mašič, Tihomir Tomašić
Izvirni znanstveni članek
Oznake: KV10.1;ionski kanali;hERG;SAR;antiproliferativno delovanje;ion channels;antiproliferative activity;
Expression of the voltage-gated potassium channel KV10.1 (Eag1) has been detected in over 70% of human cancers, making the channel a promising new target for new anticancer drug discovery. A new structural class of KV10.1 inhibitors was prepared by structural optimisation and exploration of the stru ...
Leto: 2022 Vir: Fakulteta za farmacijo (UL FFA)
Improved N-phenylpyrrolamide inhibitors of DNA gyrase as antibacterial agents for high-priority bacterial strains
Nace Zidar, Alessia Onali, Peter Peršolja, Davide Benedetto Tiz, Jaka Dernovšek, Žiga Skok, Martina Durcik, Andrej Emanuel Cotman, Martina Hrast, Anamarija Zega, Lucija Peterlin-Mašič, Janez Ilaš, Tihomir Tomašić, Danijel Kikelj
Izvirni znanstveni članek
Oznake: antibacterial;DNA gyrase;GyrB;inhibitor;N-phenylpyrrolamide;ParE;topoisomerase IV;
In this work, we describe an improved series of N-phenylpyrrolamide inhibitors that exhibit potent activity against DNA gyrase and are highly effective against high-priority gram-positive bacteria. The most potent compounds show low nanomolar IC50 values against Escherichia coli DNA gyrase, and in a ...
Leto: 2024 Vir: Fakulteta za farmacijo (UL FFA)
New N-phenylpyrrolamide inhibitors of DNA gyrase with improved antibacterial activity
Andrej Emanuel Cotman, Federica Fulgheri, Martina Piga, Peter Peršolja, Davide Benedetto Tiz, Žiga Skok, Martina Durcik, Maša Sterle, Jaka Dernovšek, Anamarija Zega, Lucija Peterlin-Mašič, Janez Ilaš, Tihomir Tomašić, Danijel Kikelj, Nace Zidar
Izvirni znanstveni članek
Oznake: N-fenilpirolamidni inhibitorji;bakterijske DNA giraze;sinteza spojin;antibakterijsko delovanje;
This study presents the discovery of a new series of N-phenylpyrrolamide inhibitors of bacterial DNA gyrase with improved antibacterial activity. The most potent inhibitors had low nanomolar IC50 values against Escherichia coli DNA gyrase (IC50; 2–20 nM) and E. coli topoisomerase IV (22i, IC50 = 143 ...
Leto: 2024 Vir: Fakulteta za farmacijo (UL FFA)
Marine strategy framework directive
Konstantinos Tsiamis, Ivan Cvitković, Marija Despalatović, Branko Dragičević, Jakov Dulčić, Ana Fortič, Janja Francé, Lovrenc Lipej, Borut Mavrič, Patricija Mozetič, Živana Ninčević Gladan, Martina Orlando-Bonaca, Monika Peterlin, Valentina Pitacco, Domen Trkov, Olja Vidjak, Ante Žuljević
Končno poročilo o rezultatih raziskav
Oznake: hidrobiologija;morski ekosistemi;neavtohtone vrste;Evropska unija;
Marine Non-Indigenous Species (NIS) are animals and plants introduced accidently or deliberately into the European seas, originating from other seas of the globe. About 800 marine non-indigenous species (NIS) currently occur in the European Union national marine waters, several of which have negativ ...
Leto: 2021 Vir: Nacionalni inštitut za biologijo (NIB)
Št. zadetkov: 9
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