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Št. zadetkov: 4
Engineered combinatorial cell device for wound healing and bone regeneration
Lucija Kadunc, Duško Lainšček, Rok Gašperšič, Petra Sušjan, Uroš Kovačič, Miha Butinar, Boris Turk, Roman Jerala, Iva Hafner Bratkovič
Izvirni znanstveni članek
Oznake: celjenje ran;regeneracija kosti;rastni faktorji;wound healing;bone regeneration;growth factors;
Growth factors are the key regulators that promote tissue regeneration and healing processes. While the effects of individual growth factors are well documented, a combination of multiple secreted growth factors underlies stem cell–mediated regeneration. To avoid the potential dangers and laborinten ...
Leto: 2023 Vir: Medicinska fakulteta (UL MF)
Endoglin (CD105) silencing mediated by shRNA under the control of Endothelin-1 promoter for targeted gene therapy of Melanoma
Nataša Tešić, Urška Kamenšek, Gregor Serša, Simona Kranjc, Monika Štimac, Urša Lampreht Tratar, Véronique Préat, Gaëlle Vandermeulen, Miha Butinar, Boris Turk, Maja Čemažar
Izvirni znanstveni članek
Oznake: melanoma;electroporation;endoglin (CD105);endothelin-1;gene therapy;
Endoglin (CD105), a transforming growth factor (TGF)-% coreceptor, and endothelin-1, a vasoconstrictor peptide, are both overexpressed in tumor endothelial and melanoma cells. Their targeting is therefore a promising therapeutic approach for melanoma tumors. The aim of our study was to construct a e ...
Leto: 2015 Vir: Fakulteta za vede o zdravju (UP FVZ)
Evaluation of novel cathepsin-X inhibitors in vitro and in vivo and their ability to improve cathepsin-B-directed antitumor therapy
Ana Mitrović, Janja Završnik, Georgy Mikhaylov, Damijan Knez, Urša Pečar Fonović, Petra Matjan-Štefin, Miha Butinar, Stanislav Gobec, Boris Turk, Janko Kos
Izvirni znanstveni članek
Oznake: cathepsin X;cathepsin B;inhibitors;cancer;antitumor therapy;invasion;
New therapeutic targets that could improve current antitumor therapy and overcome cancer resistance are urgently needed. Promising candidates are lysosomal cysteine cathepsins, proteolytical enzymes involved in various critical steps during cancer progression. Among them, cathepsin X, which acts sol ...
Leto: 2022 Vir: Fakulteta za farmacijo (UL FFA)
Prilagoditev izolatov kvasovk iz Vipavske doline za fermentacijo pivine z usmerjeno evolucijo
Eva Pavliha, Neža Čadež, Miha Tome, Lorena Butinar
Magistrsko delo
Oznake: kvasovke;Saccharomyces cerevisiae;Lachancea thermotolerans;proizvodnja piva;fermentacija pivine;poraba sladkorjev;glukoza;maltoza;usmerjena evolucija;mutageneza;selekcijski pritisk;
V magistrski nalogi smo želeli prilagoditi lokalna izolata kvasovk Saccharomyces cerevisiae in Lachancea thermotolerans na pivovarsko okolje z metodo usmerjene evolucije. Namen poskusa je bila izboljšava sevov za fermentacijo pivine preko odprave katabolne represije z glukozo in izboljšanje privzema ...
Leto: 2022 Vir: Biotehniška fakulteta (UL BF)
Št. zadetkov: 4
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